The Truth About the Drug

[Dus]

I like that theory. We don't really know Elena's maiden name or the first name of Sharon's mother. It explains why Shiho held a much higher rank in the BO than Akemi. This could be the thing Elena told Shiho on her very last tape. Certainly explains Ai's reaction upon hearing Vermouth for the first time. Only thing bothering: I'm not really sure whether the wohle "Ai'll be surprised"-thing isn't just a wide-spread rumour. Any reliable sources?

[Mr_Useless]

I like that theory. We don't really know Elena's maiden name or the first name of Sharon's mother. It explains why Shiho held a much higher rank in the BO than Akemi. This could be the thing Elena told Shiho on her very last tape. Certainly explains Ai's reaction upon hearing Vermouth for the first time. Only thing bothering: I'm not really sure whether the wohle "Ai'll be surprised"-thing isn't just a wide-spread rumour. Any reliable sources?

Aoyama himself said it in an interview, i don't really know where to find it now but it exists.
Also, "I have one more daughter" would be a believable message left in the tapes.

I'm sorry i went off-topic, everything just built up into my mind while i was writing on the topic

[Dus]

I'm gonna adopt this theory as my own if you don't mind.^^
The BO might want to use the completed APTX to revive Renya Karasuma. Don't ask me why tho.
Still, it's strange that Aoyama would tell us something like that. Basically makes Elena and Atsushi the only viable suspects.

[Tanner-kun]

I'm gonna adopt this theory as my own if you don't mind.^^
The BO might want to use the completed APTX to revive Renya Karasuma. Don't ask me why tho.
Still, it's strange that Aoyama would tell us something like that. Basically makes Elena and Atsushi the only viable suspects.

I can us this theory to support my own about the BO boss. 

[Dus]

Your theory being?

[Tanner-kun]

Your theory being?

http://forums.dctp.ws/viewtopic.php?t=3138.0 its a little old but still hasn't been proven wrong.

[sstimson]

Your theory being?

http://forums.dctp.ws/viewtopic.php?t=3138.0 its a little old but still hasn't been proven wrong.

Yet and I need to find where Ai I believe or Chris said they are Dead. Are you saying the BO is leaderless, or are they dead like I believe Akemi to be?

[Mr_Useless]

They're zombies

[mangaluva]

They're vampires. Proper vampires, murdering many and draining them of their blood.

[Suutashi]

Just some thoughts and theories I've had about APTX 4869 and wanted to see what others may think of them. I may be completely wrong about some of what I put here but still would like to read someone's input on what I have to say. I'll probably add more later when I've had more sleep and had time to go over some more of my thoughts on this subject.

1) One possibility as to why Shinichi and Haibara survived may be due to something that may have altered APTX4869 effects. When Shinichi was given the drug it was from what I can tell during an evening in Winter (in January if I'm guessing right) and thus very cold outside. Sherry/Haibara now I'm not 100% what the season was when she took the APTX 4869 herself. (I'm not going to use clothing as a reference as I've seen Conan running around outside in the snow wearing his signature outfit on. The guy either has no common sense or needs a bigger wardrobe.) However let's just say the room Sherry was being held in while she waited for the higher-ups to make a decision as to what to do with her was cold. Temperature can sometimes affect how well a drug works, which may lessen its effects or even make its effect different from what it was intended to be. However temperature would be too much of a random factor in the case of this being the one explanation as to why Shinichi and Sherry survived and their haven't been a know repeat of this in a human test subject would call for tests of APTX4869 Sherry conducted have been in a very highly controlled environment. Another possible problem is that we don't know what kind of setting the labs rats Sherry used the drug on were in when one ended up shrinking.

2) Ever looked up apoptosis online? I tried to find out if apoptosis could even lead to death. I tried to find out if someone died due to apoptosis (if it was possible that is) how you would even be able to tell, what are the signs and symptoms. I got pretty much nowhere. I've only know of one other instance where apoptosis was mentioned as a means to kill as a sort of poison in a work of fiction. It was never used so I never found out what kind of effect it has on the body that would lead to death. I really have not come up with very many ways apoptosis could be used to kill someone in a way that wouldn't arouse suspicion. Unless say if someone had been whacked upon the head every time someone was poisoned with APTX4869 (before or after being hit on the head) and because it's figured it to be death due to blunt force trauma during a police investigation a full drug/tox screen is deemed unnecessary, thus is not used. Any input as to how this could even work is more than welcome.

3) I'm not really 100% for the possibility of APTX4869 being a drug that intended to grant immortality. Heck it wouldn't really surprise me if the original reason for its development was to use controlled apoptosis as a potential cure for diseases like cancer where an insufficient amount of apoptosis is the cause of such illnesses. It many be due to the fact that something happened during the drug's development that caused its development to change from saving lives to ending them. This might likely have occurred at some point when Atsushi and Elena were alive and scientists working for the B.O. Maybe their death wasn't so much an accident as it was them trying to end their research with the end of their lives and made it look like they had died in an accident. This is a rather weak explanation as this would mean that mean their daughter, Shiho, would end up continuing the research in their stead. Why would they kill themselves because of a guilty conscience due to the results of their research when they would have to be aware of the fact that someone would continue the research anyway and the burden to bear would be placed on their own child?

[casualvgm]

my guess..
A, atsushi's aptx Drug effect? (Drug Developed by atsushi)
  Drug1. Incomplete eternal youth
      : Vermouth eat (side effect- excessive mental and physical stress->personality changes or Personality    Disorder)
  Drug2. shrink (100 percent shrink- Already make the develop.)
      : shiho, Shinichi eat.(boss's plan, Gin do not know)atsushi still alive(atsushi=boss)


B, shiho's aptx effect? (Drug Developed by shiho)
  Drug1. Poison or shrink(very less probability)

[kkakaroto9]

I want another character taking the APTX  , that would be interesting ( and the history will be even longer  )

[Shuusgirl]

1) One possibility as to why Shinichi and Haibara survived may be due to something that may have altered APTX4869 effects. When Shinichi was given the drug it was from what I can tell during an evening in Winter (in January if I'm guessing right) and thus very cold outside. Sherry/Haibara now I'm not 100% what the season was when she took the APTX 4869 herself. (I'm not going to use clothing as a reference as I've seen Conan running around outside in the snow wearing his signature outfit on. The guy either has no common sense or needs a bigger wardrobe.) However let's just say the room Sherry was being held in while she waited for the higher-ups to make a decision as to what to do with her was cold. Temperature can sometimes affect how well a drug works, which may lessen its effects or even make its effect different from what it was intended to be. However temperature would be too much of a random factor in the case of this being the one explanation as to why Shinichi and Sherry survived and their haven't been a know repeat of this in a human test subject would call for tests of APTX4869 Sherry conducted have been in a very highly controlled environment. Another possible problem is that we don't know what kind of setting the labs rats Sherry used the drug on were in when one ended up shrinking.

The temperature is an interesting theory.  I've been wondering if age might have something to do with it too.  Most of the B.O's enemies aren't going to be teenagers, so if age is a factor they probably wouldn't find out about it.  (Besides, Gin seemed like a kid trying out a new toy when he poisoned Shinichi.  He was probably just looking for an excuse to use it, explaining why he'd use the drug on a kid.)  Maybe both temperature and age are factors?

[sstimson]

How does that relate the the SHRINKING MOUSE? I believe all the mice were at the same temperature. Why only one change?

[Shuusgirl]

How does that relate the the SHRINKING MOUSE? I believe all the mice were at the same temperature. Why only one change?

Age?  It's a baby mouse?  (Mousling?  Mini mouse?  What do you call a baby mouse anyway?)
We don't really know if they were all at the same temperature.  Haibara just said that in some of the tests a couple mice shrunk.  That's why I think there's more than one factor.